Opportunity Information: Apply for SFOP0008432
The Global Biosecurity Engagement Activities opportunity is a U.S. Department of State cooperative agreement program run by the Bureau of International Security and Nonproliferation (ISN), through its Office of Cooperative Threat Reduction (CTR). It is funded with foreign assistance dollars from the Nonproliferation, Anti-terrorism, Demining and Related Programs (NADR) account and sits within the Biosecurity Engagement Program (BEP), which is part of ISN/CTR's broader Global Threat Reduction (GTR) portfolio. In practical terms, the program is designed to reduce national security risks linked to the spread or misuse of dangerous biological capabilities by helping partners around the world strengthen how they manage, secure, and govern high-risk biological materials and expertise.
The central purpose is to mitigate global biological threats by making it harder for proliferator states and non-state actors to gain access to the kinds of resources that could be turned into biological weapons. The opportunity description highlights several categories of concern: specialized biological know-how; high consequence pathogens; pathogens and toxins found on control lists such as the U.S. Select Agent List; synthetic biological materials; and dual-use equipment that has legitimate scientific or public health applications but could be repurposed for harmful ends. The program emphasis is not only on preventing theft or diversion of materials, but also on reducing the overall opportunity for misuse across the life cycle of biological work, including how materials are stored, handled, transported, accounted for, and overseen.
BEP also positions this work as directly supporting major U.S. national security and health security priorities. The notice explicitly ties program goals to multiple U.S. strategy documents, including the U.S. National Security Strategy, the U.S. National Biodefense Strategy, the U.S. Global Health Security Strategy, and a National Security Memorandum focused on U.S. global leadership in the COVID-19 response and strengthening global health security and biological preparedness. That alignment signals that proposals are expected to connect biosecurity capacity building with broader resilience and preparedness outcomes, while keeping the program's core nonproliferation and threat-reduction mission front and center.
A recurring theme in the opportunity is sustainability. BEP frames long-term durability as an underlying aim across all supported activities, meaning projects should be designed to maximize lasting impact while reducing ongoing dependence on external funding or technical support. In other words, the grant is not just looking for short-term training events or one-off purchases; it is looking for efforts that leave partner institutions with enduring systems, policies, trained personnel, and governance structures that they can maintain and improve on their own.
From the posted opportunity data, the instrument type is a cooperative agreement, which typically means substantial involvement by the U.S. government in project implementation compared with a standard grant. The opportunity number is SFOP0008432 under CFDA 19.033. The award ceiling listed is $300,000, with an anticipated 25 awards. The posting date was October 28, 2021, and the original closing date was January 31, 2022. Eligibility is described broadly as "Others" with additional eligibility details referenced in the full announcement, suggesting the program may consider a range of applicant types depending on the specific rules in the notice (commonly including organizations such as nonprofits, universities, research institutions, and potentially other entities that can carry out international biosecurity engagement work).
Overall, this funding opportunity supports projects that help reduce the risk of biological weapons development or biological incident threats by strengthening biosecurity and biosafety practices, controlling access to sensitive materials and know-how, and reinforcing responsible governance of dual-use life science capabilities. The intent is to achieve measurable threat reduction in ways that endure after the period of performance, supporting both immediate security needs and longer-term global health security and biological preparedness goals.Apply for SFOP0008432
- The Department of State, Bureau of International Security-Nonproliferation in the other (see text field entitled explanation of other category of funding activity for clarification) sector is offering a public funding opportunity titled "Global Biosecurity Engagement Activities" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 19.033.
- This funding opportunity was created on Oct 28, 2021.
- Applicants must submit their applications by Jan 31, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- The number of recipients for this funding is limited to 25 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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| Countering the People's Republic of China Military Civil Fusion (MCF) Strategy and Balancing Risks and Rewards of Emerging Technologies with WMD Applications Apply for SFOP0008433 Funding Number: SFOP0008433 Agency: Department of State, Bureau of International Security-Nonproliferation Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $300,000 |
| Ambassadors Fund for Cultural Preservation Apply for BR FY22 NOFO001 Funding Number: BR FY22 NOFO001 Agency: Department of State, U.S. Mission to Brazil Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $500,000 |
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| FY 2021 Assistance to Firefighters Grant Program (AFG) Apply for DHS 21 GPD 044 00 98 Funding Number: DHS 21 GPD 044 00 98 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $9,000,000 |
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| Alumni Small Grants Program 2022 Apply for HRV2022 NOFO001 Funding Number: HRV2022 NOFO001 Agency: Department of State, U.S. Mission to Croatia Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $25,000 |
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| Bureau of Democracy, Human Rights and Labor Request for Statements of Interest: FY21 China Programs Apply for SFOP0008439 Funding Number: SFOP0008439 Agency: Department of State, Bureau of Democracy Human Rights and Labor Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $1,500,000 |
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| Bureau of Democracy, Human Rights and Labor Request for Statements of Interest: FY21 China Programs Apply for SFOP0008442 Funding Number: SFOP0008442 Agency: Department of State, Bureau of Democracy Human Rights and Labor Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $1,500,000 |
| U.S. Embassy Cotonou PDS Request for Statements of Interest: Annual Program Statement Apply for PAS SGP FY22 01 Funding Number: PAS SGP FY22 01 Agency: Department of State, U.S. Mission to Benin Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $20,000 |
| Public Diplomacy Small Grants Program Apply for PDS CHISINAU FY22 03 Funding Number: PDS CHISINAU FY22 03 Agency: Department of State, U.S. Mission to Moldova Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $50,000 |
| U.S. Mission to South Africa Public Affairs Section Annual Program Statement 2022 Apply for PAS ZAF FY22 01 Funding Number: PAS ZAF FY22 01 Agency: Department of State, U.S. Mission to South Africa Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $25,000 |
| 2022 Iraq, Jordan, Lebanon, and Turkey CN Apply for SFOP0008443 Funding Number: SFOP0008443 Agency: Department of State, Bureau of Population Refugees and Migration Category: Other (see text field entitled Explanation of Other Category of Funding Activity for clarification) Funding Amount: $4,000,000 |
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